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MYP_139448
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Basic Information
Myxinidin G1A
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
12 amino acids
C62H100N16O17
Standard
Sequence
AIHDILKYGKPS
Physicochemical Analysis
1341.55 Da
8.55
0.88
0.64
0.0734
-0.33
0.57
0.07
24.04
105.83
0.0833
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
533.11
-3.33
18.0
19.0
43.0
95.0
3.0
11.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0004718 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Myxinidin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Staphylococcus aureus ATCC 6538
10 μM
MIC
PaperStructural insights into and activity analysis of the antimicrobial peptide myxinidin. PMID24957834 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24957834/
RECORD: Rec_0009208 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Human RBC
Hemolysis
PMID24957834 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24957834/
RECORD: Rec_0012270 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Klebsiella pneumoniae
50 μM
MIC
PMID24957834 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24957834/
RECORD: Rec_0024354 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Hemolytic
human red blood cells, but in general, negligible hemolytic activity is observed even at 100 μM and 200 μM peptide
PaperStructural insights into and activity analysis of the antimicrobial peptide myxinidin. Antimicrob Agents Chemother. 2014 Sep;58(9):5280-90. doi: 10.1128/AAC.02395-14. PMID: 24957834. PMID24957834 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24957834/
RECORD: Rec_0045377 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus
10 μM
MIC
PMID24957834 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24957834/
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