Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Standard StatusStandard

Sequence Length160 amino acids

Chemical FormulaC792H1263N217O226S10

DescriptionStandard

        MIFLTLAFIVYGLLTQGNKAAWRRPIPKCWKNSLGYCRVRCQEEERYIYLCKNKVSCCIHRTLSEDKLPSGPPIHTVTRVIPSFKVPVNSSVTRLTDNKNWDANDSKTPTGTIVNPAGIVKMPTGTTVNPAGIGKTPTTTAPIYSWATNTKPFTMMPNTT
    

Molecular Weight17761.47 Da

Isoelectric Point (pI)9.73

Net Charge (pH 7.0)11.61

Net Charge (pH 7.4) 11.17

Charge Density (pH 7.0) 0.0726

GRAVY Index-0.28

Hydrophobic Moment 0.68

Boman Index0.02

Instability Index35.37

Aliphatic Index 73.69

Aromaticity 0.0813

Extinction Coeff. Reduced 29450.00

Extinction Coeff. Oxidized 29825.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7073.18

LogP -74.33

H-bond Donors 251.0

H-bond Acceptors 250.0

Rotatable Bonds 562.0

Heavy Atoms 1245.0

Ring Count 34.0

Amide Bonds 172.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0265033 VERIFIED: NO

Provenance & Taxonomy

OrganismMus spicilegus [Animal]

FamilyDefensin

Structure & Mods

Configdisulfide-stabilized peptide with linear backbone [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin

MethodQualitative functional evidence