Peptide Database

Peptide NameFungal defensin copsin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive ▸ Anti-Listeria

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length184 amino acids

Chemical FormulaC794H1296N234O264S19

DescriptionStandard

        MKLSTSLLAIVAVASTFIGNALSATTVPGCFAECIDKAAVAVNCAAGDIDCLQASSQFATIVSECVATSDCTALSPGSASDADSINKTFNILSGLGFIDEADAFSAADVPEERDLTGLGRVLPVEKRQNCPTRRGLCVTSGLTACRNHCRSCHRGDVGCVRCSNAQCTGFLGTTCTCINPCPRC
    

Molecular Weight18953.43 Da

Isoelectric Point (pI)5.29

Net Charge (pH 7.0)-3.48

Net Charge (pH 7.4) -4.08

Charge Density (pH 7.0) -0.0189

GRAVY Index0.25

Hydrophobic Moment 0.69

Boman Index0.09

Instability Index49.15

Aliphatic Index 81.74

Aromaticity 0.0380

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 1125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7926.30

LogP -107.75

H-bond Donors 294.0

H-bond Acceptors 282.0

Rotatable Bonds 615.0

Heavy Atoms 1311.0

Ring Count 16.0

Amide Bonds 195.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0001111 VERIFIED: YES

Provenance & Taxonomy

OrganismCoprinopsis cinerea [Fungus]

FamilyDefensin

Tax ID240176

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

N-TermPyroglutamate

Other ModsN-terminal pyroglutamate

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defensin Antilisterial Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetBacillus subtilis (Gram-positive)

RECORD: Rec_0011654 VERIFIED: YES

Provenance & Taxonomy

OrganismCoprinopsis cinerea [Fungus]

FamilyDefensin

Tax ID240176

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

N-TermPyroglutamate

Other ModsN-terminal pyroglutamate

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defensin Antilisterial Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetListeria (Gram-positive)

RECORD: Rec_0140936 VERIFIED: YES

Provenance & Taxonomy

OrganismCoprinopsis cinerea [Fungus]

FamilyDefensin

Tax ID240176

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

N-TermPyroglutamate

Other ModsN-terminal pyroglutamate

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defensin Antilisterial Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetEnterococcus (Gram-positive)

RECORD: Rec_0278520 VERIFIED: YES

Provenance & Taxonomy

OrganismCoprinopsis cinerea [Fungus]

FamilyDefensin

Tax ID240176

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

N-TermPyroglutamate

Other ModsN-terminal pyroglutamate

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defensin Antilisterial Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetPseudomonas aeruginosa (Gram-negative)

RECORD: Rec_0422251 VERIFIED: YES

Provenance & Taxonomy

OrganismCoprinopsis cinerea [Fungus]

FamilyDefensin

Tax ID240176

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

N-TermPyroglutamate

Other ModsN-terminal pyroglutamate

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defensin Antilisterial Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetB. anthracis (Gram-positive)