‹ ›
MYP_139275
← PREVIOUS NEXT → BACK
Basic Information
Brevinin-1CG5 (Frogs, amphibians, animals)
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Venom / Toxin ▸ General toxin ▸ Toxicity
Standard
24 amino acids
C123H207N29O27S3
Standard
Sequence
FLPMLAGLAANFLPKIVCKITKKC
Physicochemical Analysis
2620.33 Da
9.70
3.74
3.50
0.1557
0.95
0.68
0.31
5.62
122.08
0.0833
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
882.44
-2.94
31.0
34.0
86.0
182.0
4.0
24.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0272497 VERIFIED: YES
Provenance & Taxonomy
Amolops chunganensis [Animal]
Brevinin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Rhodococcus rhodochrous
0.6 μM
MIC
PMID22951323 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22951323/
RECORD: Rec_0281689 VERIFIED: YES
Provenance & Taxonomy
Amolops chunganensis [Animal]
Brevinin
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Pseudomonas aeruginosa (CGMCC 1.50)
75 μM
MIC
PMID22951323 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22951323/
RECORD: Rec_0294464 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 37.5%, E 0.0%, T 29.2%, C 33.3% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Toxic Antimicrobial Antifungal Anti-Gram-positive Cytotoxic Anti-Gram-negative
PaperCAMP: Collection of sequences and structures of antimicrobial peptides PMID24265220 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24265220/
RECORD: Rec_0309804 VERIFIED: YES
Provenance & Taxonomy
Amolops chunganensis [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
18-24
Bio-Activity Profile
Antimicrobial Antifungal
Candida albicans ATCC 10231
37.5 μM
MIC
PaperCharacterization of diverse antimicrobial peptides in skin secretions of Chungan torrent frog Amolops chunganensis
RECORD: Rec_0339669 VERIFIED: YES
Provenance & Taxonomy
Amolops chunganensis [Animal]
Brevinin
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Staphylococcus carnosus KHS (IS)
1.2 μM
MIC
PMID22951323 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22951323/
FIRST PREV 1 2 3 4 5 6 NEXT LAST
Showing 5 records on this page · Page 4 of 6