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MYP_139264
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Basic Information
WAM2
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Standard
36 amino acids
C192H321N61O49
Standard
Sequence
KRGLWESLKRKATKLGDDIRNTLRNFKIKFPVPRQG
Physicochemical Analysis
4267.98 Da
11.49
7.76
7.54
0.2155
-1.07
0.79
-0.37
48.77
75.83
0.0833
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1847.51
-16.89
66.0
57.0
149.0
302.0
6.0
38.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0010459 VERIFIED: YES
Provenance & Taxonomy
Macropus eugenii [Animal]
Cathelicidin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Salmonella enterica ATCC 14028
1.58 μM
MIC
PMID21912615 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21912615/
RECORD: Rec_0044251 VERIFIED: YES
Provenance & Taxonomy
Tammar wallaby [Animal]; Mammalia [Animal]
33208; 40674
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID21912615 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21912615/
RECORD: Rec_0094967 VERIFIED: YES
Provenance & Taxonomy
Macropus eugenii [Animal]
Cathelicidin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Strep. pyogenes ATCC 19615
0.39 μM
MIC
PMID21912615 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21912615/
RECORD: Rec_0120561 VERIFIED: YES
Provenance & Taxonomy
Macropus eugenii [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0175407 VERIFIED: YES
Provenance & Taxonomy
Macropus eugenii [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Staphylococcus aureus ATCC 25923
1.39 μM
MIC
PaperAncient antimicrobial peptides kill antibiotic-resistant pathogens: Australian mammals provide new options
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