Peptide Database

Peptide Nameprokineticin-1

Function Ontology

Neurological / Signaling ▸ Signaling peptide

Standard StatusStandard

Sequence Length86 amino acids

Chemical FormulaC413H658N132O115S10

DescriptionStandard

        AVITGACERDIQCGAGTCCAISLWLRGLRLCTPLGREGEECHPGSHKIPFLRKRQHHTCPCSPSLLCSRFPDGRYRCFRDLKNANF
    

Molecular Weight9633.11 Da

Isoelectric Point (pI)8.95

Net Charge (pH 7.0)6.06

Net Charge (pH 7.4) 5.50

Charge Density (pH 7.0) 0.0704

GRAVY Index-0.33

Hydrophobic Moment 0.75

Boman Index-0.10

Instability Index50.92

Aliphatic Index 68.14

Aromaticity 0.0698

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7615.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3947.41

LogP -43.48

H-bond Donors 150.0

H-bond Acceptors 135.0

Rotatable Bonds 311.0

Heavy Atoms 670.0

Ring Count 17.0

Amide Bonds 89.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0050424 VERIFIED: NO

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyGtoPdb endogenous peptide ligand

Tax ID10090

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidereported in GtoPdb PTM annotation

Other ModsThere are 5 disulfide bonds formed between cysteine residues at positions 7 and 19, 13 and 31, 18 and 59, 41 and 67, 61 and 77.

Bio-Activity Profile

Function

Signaling peptide

TargetPKR1 (Mouse); PKR2 (Mouse)