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MYP_139219
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Basic Information
Antifungal peptide 1
Antimicrobial
Antimicrobial ▸ Anti-biofilm ▸ Biofilm inhibition
Antimicrobial ▸ Antifungal
Antimicrobial ▸ Antifungal ▸ Fungicidal activity
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
11 amino acids
C49H80N14O17S3
Standard
Sequence
LMCTHPLDCSN
Physicochemical Analysis
1233.44 Da
5.08
-1.17
-1.45
-0.1065
0.11
0.12
0.10
36.11
70.91
0.0000
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
495.06
-5.85
18.0
20.0
37.0
83.0
2.0
11.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0148805 VERIFIED: YES
Provenance & Taxonomy
Trapa natans [Plant]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
C. tropicalis
32 μg/mL
MIC
RECORD: Rec_0154548 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0226894 VERIFIED: YES
Provenance & Taxonomy
Trapa natans [Plant]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antibiofilm Antifungal
Candida tropicalis
12.982 μM
XTT assay
RECORD: Rec_0291088 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antifungal
PaperBaAMPs: the database of biofilm-active antimicrobial peptides PMID25760404 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25760404/
RECORD: Rec_0314708 VERIFIED: YES
Provenance & Taxonomy
Trapa natans [Animal]
Defensin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
3-9
Bio-Activity Profile
Antimicrobial Antifungal
red blood cells/erythrocytes
32 μg/mL
Hemolysis
PMID21736910 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21736910/
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