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MYP_139180
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Basic Information
Angiotensin 1-7
Annotation / Sequence feature ▸ Secretory pathway ▸ Secreted protein
Antiviral ▸ Anti-Coronavirus ▸ Anti-SARS-CoV-2
Cardiovascular
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide
Cardiovascular ▸ Vascular tone modulation ▸ Vasoconstrictor activity
Cardiovascular ▸ Vascular tone modulation ▸ Vasodilatory activity
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Hormonal / Endocrine ▸ Hormone peptide
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Immunology ▸ Inflammation modulation ▸ Anti-inflammatory
Membrane / Ion-channel modulation ▸ Sodium channel modulation ▸ Sodium channel inhibitor
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Regulatory peptide ▸ Cell signaling / Growth factor signaling ▸ Growth factor activity
Reproductive biology ▸ Reproductive modulation
Wound healing/Regeneration ▸ Angiogenesis modulation ▸ Angiogenic
Standard
7 amino acids
C41H62N12O11
Standard
Sequence
DRVYIHP
Physicochemical Analysis
899.00 Da
6.74
-0.15
-0.41
-0.0218
-0.77
0.37
-0.14
0.54
97.14
0.1429
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
377.24
-1.83
13.0
12.0
25.0
64.0
3.0
6.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0164965 VERIFIED: YES
Provenance & Taxonomy
Ovis aries [Animal]
Angiotensin
9940
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Vasoactive Vasodilator Vasoconstrictor Cardiovascular Metabolic regulation Physiological regulation Growth regulation Development regulation
Experimental: 10±1 seconds; /10 seconds; Mammalian: 1.1 hour; Yeast: 3 min; E. coli: >10 hour
PaperSource-linked PubMed record(s) for Angiotensin 1-7 (Ovis aries): PMID 3081342##9740616 PMID3081342;9740616 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/3081342/
RECORD: Rec_0167501 VERIFIED: YES
Provenance & Taxonomy
Callithrix jacchus [Animal]
Angiotensin
9483
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Vasoactive Vasodilator Vasoconstrictor Cardiovascular Metabolic regulation Physiological regulation Growth regulation Development regulation
Experimental: 10±1 seconds; /10 seconds; Mammalian: 1.1 hour; Yeast: 3 min; E. coli: >10 hour
PaperSource-linked PubMed record(s) for Angiotensin 1-7 (Callithrix jacchus): PMID 10598135##9740616 PMID10598135;9740616 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10598135/
RECORD: Rec_0183636 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Angiotensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antihypertensive
Radioimmunoassay and HPLC
Blood sample of normotensive Sprague-Dawley rat, in vivo; 10 s
PMID9740616 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9740616/
RECORD: Rec_0189217 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Angiotensin peptide
9606
Structure & Mods
branched peptide architecture [Branched]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Immunomodulatory Anti-inflammatory Anti-SARS-CoV-2
Severe acute respiratory syndrome coronavirus 2
PMID36579082 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/36579082/
RECORD: Rec_0209931 VERIFIED: YES
Provenance & Taxonomy
Gorilla gorilla gorilla [Animal]
Serpin
9595
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Secreted protein
PMID3081342 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/3081342/
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