Peptide Database

Peptide NameBrevinin-2SN2

Function Ontology

Antimicrobial

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Anti-Candida

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Standard StatusStandard

Sequence Length75 amino acids

Chemical FormulaC355H578N90O113S6

DescriptionStandard

        MFTMKKSLLFLFFLGTISLSFCEEERGADEDDGGEMTEEEKRGVLDTLKNVAIGVAKGAGTGVLKALLCQLDKSC
    

Molecular Weight8107.31 Da

Isoelectric Point (pI)4.68

Net Charge (pH 7.0)-4.51

Net Charge (pH 7.4) -4.79

Charge Density (pH 7.0) -0.0601

GRAVY Index0.06

Hydrophobic Moment 0.68

Boman Index0.08

Instability Index24.75

Aliphatic Index 89.73

Aromaticity 0.0667

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3275.81

LogP -30.72

H-bond Donors 116.0

H-bond Acceptors 115.0

Rotatable Bonds 285.0

Heavy Atoms 564.0

Ring Count 5.0

Amide Bonds 76.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0149740 VERIFIED: YES

Provenance & Taxonomy

OrganismSylvirana spinulosa [Animal]

FamilyBrevinin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Anti-Candida Cytolytic Hemolytic

RECORD: Rec_0216948 VERIFIED: NO