Peptide Database

Peptide NameScorpine (RScp)

Function Ontology

Antimicrobial

Antiparasitic ▸ Antimalarial

Antiparasitic ▸ General antiparasitic ▸ Antiparasitic

Standard StatusStandard

Sequence Length75 amino acids

Chemical FormulaC356H578N106O108S12

DescriptionStandard

        GWINEEKIQKKIDERMGNTVLGRMAKAIVHKMAKNEFQCMANMDMLGNCEKHCQTSGEKGYCHGTKCKCGTPLSY
    

Molecular Weight8455.82 Da

Isoelectric Point (pI)8.80

Net Charge (pH 7.0)3.97

Net Charge (pH 7.4) 3.50

Charge Density (pH 7.0) 0.0529

GRAVY Index-0.69

Hydrophobic Moment 0.62

Boman Index-0.12

Instability Index20.89

Aliphatic Index 49.47

Aromaticity 0.0533

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8855.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3498.72

LogP -37.96

H-bond Donors 125.0

H-bond Acceptors 127.0

Rotatable Bonds 297.0

Heavy Atoms 582.0

Ring Count 9.0

Amide Bonds 82.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0038021 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyScorpine

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Antiparasitic Antimalarial

TargetPlasmodium falciparum FCR3

Activity5 μM

MethodPercent inhibition; Microscopy (Giemsa staining)

RECORD: Rec_0127395 VERIFIED: YES