Peptide Database

Peptide NameMacromomycin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length139 amino acids

Chemical FormulaC559H914N154O190S5

DescriptionStandard

        MQKKLIAKAAAAFALAGGLTLASQAGASAAGTVSVTPATGLTSGATVTVSATGLTANLEHFVGLCGTVGGQYACDATGVVSVTTNASGAASTPLTVKKTFTGTVGGGGSVTVDCGAVQCVIGVYNADGSAGASTNVAFS
    

Molecular Weight12992.48 Da

Isoelectric Point (pI)7.65

Net Charge (pH 7.0)0.55

Net Charge (pH 7.4) 0.21

Charge Density (pH 7.0) 0.0039

GRAVY Index0.59

Hydrophobic Moment 0.47

Boman Index0.31

Instability Index4.00

Aliphatic Index 85.04

Aromaticity 0.0432

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3230.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5402.06

LogP -81.29

H-bond Donors 194.0

H-bond Acceptors 197.0

Rotatable Bonds 416.0

Heavy Atoms 908.0

Ring Count 9.0

Amide Bonds 146.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0140622 VERIFIED: NO

Provenance & Taxonomy

OrganismAmycolatopsis sp. YIM 10 [Bacterium]

FamilyNeocarzinostatin

Structure & Mods

Configlinear polypeptide/propeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Non-hemolytic Non-ribosomal