Peptide Database

Peptide NameMERS-CoV-HR1P

Function Ontology

Antiviral

Standard StatusStandard

Sequence Length42 amino acids

Chemical FormulaC192H308N58O65S

DescriptionStandard

        ANKFNQALGAMQTGFTTTNEAFRKVQDAVNNNAQALSKLASE
    

Molecular Weight4500.91 Da

Isoelectric Point (pI)8.54

Net Charge (pH 7.0)0.80

Net Charge (pH 7.4) 0.60

Charge Density (pH 7.0) 0.0192

GRAVY Index-0.53

Hydrophobic Moment 0.74

Boman Index-0.06

Instability Index9.32

Aliphatic Index 60.71

Aromaticity 0.0714

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2060.56

LogP -28.69

H-bond Donors 68.0

H-bond Acceptors 67.0

Rotatable Bonds 154.0

Heavy Atoms 316.0

Ring Count 3.0

Amide Bonds 51.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0034840 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Protein-binding Peptide-protein interaction Structural binding Coronavirus HR1 model peptide

TargetMERS-CoV HR2-derived fusion-inhibitor peptides / EK1

MethodNative PAGE and circular-dichroism analysis of HR1P-HR2P/EK1 complex