Peptide Database

Peptide NameColicin-D

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length751 amino acids

Chemical FormulaC3572H5680N1020O1111S22

DescriptionStandard

        MPQDIAEEEMVVLSDPPPQLNAGSGAVGNGQLPGVYSGFSPQETGRLNGLGYDTNPTGPVGSTNINIYSAPDISRMGVQNRLEPRPDPSGQTLGIGFSTVLDEYLNKSDNDHCPVCGRENCKYWKNDRVLLNSMRKNENNLRGNLFGAKLPLQVTVRNTATRFNHSLPNVLYPLINIPGMVTAPPSAFSKENFKNLMYLRKKMAHFMKLTEEERRALQIALYRHSAPDTYNPAFDQLDRGDFRNGVKTLYGLMADTEQNRYVLSVLISELEKRGLSDDGINQLKTELAAKTPEAKAKAEEARKAEEARKAEEARRAEEARKAEEARKAEEARKAEAARKALFAKAGVLDAPVYTPGMIKAANAAMATAGVMVLNRAGGMVQLSTWINSVMTSASELAGWVSGGVWRGAVDVSRVATLSAVAPAVGAFVVGFWPGKAGESQSDIDKLLGRDLTQMFTVPASLVAAGKTQIQPEMTTVDLPVRGFIRRGNNGQQEVILVKTGTGGVSATVPVYRPVRDEKTGLDRITLPAVAGAPGRTILINPGAAPSGPWHTGNPAPAAPVTPVHTGTEIKQADSIVTTTFPADDMPLQDFIYWQPDATGTGVEPVYVMLSGPYGETNAKGQYSGRDYNTGKAGGPIQNLDWKTATIDRAGVDKVKLHTGRFGESPDNKVMIDRLEKILKGEVQPTDTDKRFYTHEIRELERYRAVGVPDGISPDDDGATWNNTHTATLEDYKLSSDRSLLYTPEALKAGDE
    

Molecular Weight81394.91 Da

Isoelectric Point (pI)6.25

Net Charge (pH 7.0)-3.62

Net Charge (pH 7.4) -4.54

Charge Density (pH 7.0) -0.0048

GRAVY Index-0.45

Hydrophobic Moment 0.73

Boman Index-0.03

Instability Index32.95

Aliphatic Index 76.28

Aromaticity 0.0652

Extinction Coeff. Reduced 82280.00

Extinction Coeff. Oxidized 82405.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0323992 VERIFIED: YES

Provenance & Taxonomy

OrganismSerratia marcescens [Bacterium]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibiotic Bacteriocin Non-hemolytic Non-ribosomal

TargetEscherichia coli (Gram-negative)