Peptide Database

Peptide NameEndolysin (EC 3.2.1.17) (Lysis protein) (Lysozyme) (Muramidase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme / Catalytic activity ▸ Hydrolase ▸ Glycosidase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length150 amino acids

Chemical FormulaC757H1221N225O212S6

DescriptionStandard

        MKVSKRGIELIKHFEGVRSRPYRCAANLYTVGVGHLIGDGKHLPDSWNRTFTQEEIDGLLKSDLNRFELGVSKMLPNVRLRQCEFDALVSWSFNLGLGQFQRSTLRQALLRGDKEAAIESLLKYCRAGGRVLKGLQLRREAEAKMFKSGY
    

Molecular Weight17058.56 Da

Isoelectric Point (pI)9.86

Net Charge (pH 7.0)9.75

Net Charge (pH 7.4) 9.30

Charge Density (pH 7.0) 0.0650

GRAVY Index-0.39

Hydrophobic Moment 0.82

Boman Index-0.10

Instability Index44.28

Aliphatic Index 89.07

Aromaticity 0.0867

Extinction Coeff. Reduced 16960.00

Extinction Coeff. Oxidized 17085.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7140.12

LogP -67.58

H-bond Donors 257.0

H-bond Acceptors 231.0

Rotatable Bonds 588.0

Heavy Atoms 1200.0

Ring Count 21.0

Amide Bonds 160.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0382553 VERIFIED: NO

Provenance & Taxonomy

Organismuncultured Caudovirales phage [Virus]

FamilyGlycosyl hydrolase 24

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Glycosidase Hydrolase Cytolytic Non-hemolytic