Peptide Database

Peptide NameBeta-defensin 124 (Beta-defensin 24, DEFB-24; Defensin, beta 124; Human, mammals, animals)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length49 amino acids

Chemical FormulaC251H379N67O72S7

DescriptionStandard

        EFKRCWKGQGACQTYCTRQETYMHLCPDASLCCLSYALKPPPVPKHEYE
    

Molecular Weight5711.56 Da

Isoelectric Point (pI)7.84

Net Charge (pH 7.0)0.96

Net Charge (pH 7.4) 0.58

Charge Density (pH 7.0) 0.0196

GRAVY Index-0.68

Hydrophobic Moment 0.40

Boman Index-0.09

Instability Index79.42

Aliphatic Index 43.88

Aromaticity 0.1224

Extinction Coeff. Reduced 11460.00

Extinction Coeff. Oxidized 11835.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2215.04

LogP -19.71

H-bond Donors 81.0

H-bond Acceptors 82.0

Rotatable Bonds 178.0

Heavy Atoms 397.0

Ring Count 14.0

Amide Bonds 51.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0220543 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyDefensin

Tax ID9606

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitycanonical L-amino-acid peptide [L]

DisulfideDisulfide bond(s) reported

Bio-Activity Profile

Function

Antimicrobial Antibacterial

RECORD: Rec_0292757 VERIFIED: NO