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MYP_138976
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Basic Information
Temporin-Eca (Frogs, amphibians, animals)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Antimicrobial ▸ Antifungal
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
10 amino acids
C51H84N10O11
Standard
Sequence
FLPGLLAGLL
Physicochemical Analysis
1013.27 Da
5.53
-0.24
-0.44
-0.0240
2.12
0.23
0.82
28.26
205.00
0.1000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
316.43
1.02
10.0
11.0
30.0
72.0
2.0
9.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0055740 VERIFIED: YES
Provenance & Taxonomy
Euphlyctis cyanophlyctis [Animal]
Temporin
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Hemolytic
human red blood cells
Evidence URLhttps://dramp.cpu-bioinfor.org/browse/All_Information.php?dataset=General&id=DRAMP01832
RECORD: Rec_0067700 VERIFIED: YES
Provenance & Taxonomy
Euphlyctis cyanophlyctis [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial
Staphylococcus aureus PTCC1431
10.6 μM
MIC
PaperIdentification and Characterization of Novel Antibacterial Peptides from Skin Secretions of Euphlyctis cyanophlyctis
RECORD: Rec_0073408 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-Gram-negative
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0110848 VERIFIED: YES
Provenance & Taxonomy
Euphlyctis cyanophlyctis [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Candida albicans
100 μM
MIC
PMID28105725 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28105725/
RECORD: Rec_0119815 VERIFIED: YES
Provenance & Taxonomy
Euphlyctis cyanophlyctis [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial
Micrococcus luteus PTCC1625
8.3 μM
MIC
PaperIdentification and Characterization of Novel Antibacterial Peptides from Skin Secretions of Euphlyctis cyanophlyctis
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