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MYP_138964
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Basic Information
Phyllokinin
Antimicrobial
Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide
Cardiovascular ▸ Vascular tone modulation ▸ Vasodilatory activity
Regulatory peptide ▸ Biological modulation
Standard
11 amino acids
C65H93N17O14
Standard
Sequence
RPPGFSPFRIY
Physicochemical Analysis
1336.54 Da
10.84
1.76
1.55
0.1599
-0.56
0.33
-0.03
101.56
35.45
0.2727
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
492.21
-2.61
17.0
16.0
35.0
96.0
6.0
10.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0078347 VERIFIED: NO
Provenance & Taxonomy
Phyllomedusa hypochondrialis [Animal]; Phasmahyla jandaia [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0098196 VERIFIED: YES
Provenance & Taxonomy
Pithecopus hypochondrialis [Animal]
Phyllokinin
317381
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
3:4-hydroxyproline; 11:Sulfotyrosine
Bio-Activity Profile
Vasoactive Vasodilator Receptor modulation
Mammalian: 1 hour; Yeast: 2 min; E. coli: 2 min
PaperSource-linked PubMed record(s) for Phyllokinin (Pithecopus hypochondrialis): PMID 17120273 PMID17120273 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17120273/
RECORD: Rec_0171697 VERIFIED: NO
Provenance & Taxonomy
Phyllomedusa rohdei [Animal]
Phyllokinin
Structure & Mods
ribosomal mature linear peptide [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
Bio-Activity Profile
-
Evidence URLhttps://www.uniprot.org/uniprotkb/Q7LZ52/entry
RECORD: Rec_0193801 VERIFIED: YES
Provenance & Taxonomy
Pithecopus rohdei [Animal]
Phyllokinin
8394
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
11:Sulfotyrosine
Bio-Activity Profile
Vasoactive Vasodilator Receptor modulation
Mammalian: 1 hour; Yeast: 2 min; E. coli: 2 min
PMID5970899 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/5970899/
RECORD: Rec_0233413 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa sauvagii [Animal]
Phyllokinin
8395
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
11:Sulfotyrosine
Bio-Activity Profile
Vasoactive Vasodilator Receptor modulation
vitro relaxation of rat arterial smooth muscle
Mammalian: 1 hour; Yeast: 2 min; E. coli: 2 min
PaperSource-linked PubMed record(s) for Phyllokinin (Phyllomedusa sauvagei): PMID 14612182 PMID14612182 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14612182/
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