Peptide Database

Peptide NameProgonadoliberin-2

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Reproductive biology ▸ Reproductive modulation

Standard StatusStandard

Sequence Length62 amino acids

Chemical FormulaC322H509N93O92S2

DescriptionStandard

        QHWSHGWYPGGKREIDIYDTSEVSGEIKLCEAGKCSYLRPQGRNILKTILLDALIRDFQKRK
    

Molecular Weight7219.18 Da

Isoelectric Point (pI)9.07

Net Charge (pH 7.0)2.92

Net Charge (pH 7.4) 2.57

Charge Density (pH 7.0) 0.0471

GRAVY Index-0.72

Hydrophobic Moment 0.74

Boman Index-0.14

Instability Index50.23

Aliphatic Index 83.39

Aromaticity 0.0968

Extinction Coeff. Reduced 15470.00

Extinction Coeff. Oxidized 15595.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3028.23

LogP -26.80

H-bond Donors 109.0

H-bond Acceptors 99.0

Rotatable Bonds 245.0

Heavy Atoms 509.0

Ring Count 12.0

Amide Bonds 65.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0041488 VERIFIED: YES

Provenance & Taxonomy

OrganismRutilus rutilus [Animal]

FamilyProgonadoliberin

Tax ID48668

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

N-TermPyroglutamate

Other Mods10:Glycine amide

Bio-Activity Profile

Function

Hormone Endocrine Reproductive regulator

Half-LifeMammalian: 0.8 hour; Yeast: 10 min; E. coli: >10 hour