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MYP_138916
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Basic Information
Caerin 4.2
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
23 amino acids
C105H176N28O32
Standard
Sequence
GLWQKIKSAAGDLASGIVEAIKS
Physicochemical Analysis
2342.69 Da
8.50
0.76
0.55
0.0331
0.25
0.58
0.20
1.40
114.78
0.0435
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
975.75
-9.38
34.0
33.0
81.0
165.0
2.0
23.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0360795 VERIFIED: YES
Provenance & Taxonomy
Australian green tree [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Bacillus cereus
>100 μg/mL
MIC
PaperPeptides from Australian frogs. The structures of the caerins from Litoria caerula.
RECORD: Rec_0363710 VERIFIED: YES
Provenance & Taxonomy
Australian green tree [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Pasteurella multocida
>100 μg/mL
MIC
PaperPeptides from Australian frogs. The structures of the caerins from Litoria caerula.
RECORD: Rec_0381653 VERIFIED: YES
Provenance & Taxonomy
Australian green tree [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
E.clocae
>100 μg/mL
MIC
PaperPeptides from Australian frogs. The structures of the caerins from Litoria caerula.
RECORD: Rec_0413286 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
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