Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length183 amino acids

Chemical FormulaC923H1398N208O283S6

DescriptionStandard

        IDDLAEVDYSLNSLPAVFRQFIDLDLKGIVYPAGNYTGSPYVAAPFTIPAQSDSMLYLAFSEYFFQTSSFAYYTAGAFNITIAEETCSYFNISTEIFGSIIPEVAKYSVTPYPVMLKLTATEIPTISLEQDSFTVEIQGSMEVFAVLPDSTTQSLFTMNIAANTSLALNIFDQKLVGSLCLNR
    

Molecular Weight20128.59 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-13.24

Net Charge (pH 7.4) -13.51

Charge Density (pH 7.0) -0.0723

GRAVY Index0.31

Hydrophobic Moment 0.62

Boman Index0.25

Instability Index45.44

Aliphatic Index 94.92

Aromaticity 0.1366

Extinction Coeff. Reduced 16390.00

Extinction Coeff. Oxidized 16515.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7785.13

LogP -83.91

H-bond Donors 266.0

H-bond Acceptors 276.0

Rotatable Bonds 638.0

Heavy Atoms 1420.0

Ring Count 35.0

Amide Bonds 197.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0336133 VERIFIED: NO

Provenance & Taxonomy

OrganismChroicocephalus maculipennis (Brown-hooded gull) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria