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MYP_138876
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Basic Information
Unnamed
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Standard
5 amino acids
C23H41N7O8
Standard
Sequence
QKTAP
Physicochemical Analysis
543.61 Da
8.75
0.76
0.55
0.1518
-1.58
0.39
-0.33
46.52
20.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
260.27
-3.36
8.0
9.0
16.0
38.0
1.0
5.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0076248 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
kappa-Casein-derived
9606
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
ACE inhibitory Antihypertensive
Angiotensin-converting enzyme (ACE)
30 μM
IC50
PaperInhibition of angiotensin-converting enzyme by synthetic peptide fragments of human kappa-casein | Kohmura, M. et al. | DOI: 10.1080/00021369.1989.10869621 Evidence URLhttps://www.uniprot.org/uniprotkb/P07498/entry
RECORD: Rec_0160183 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Casein-derived peptide
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Enzyme inhibitory ACE inhibitory
Angiotensin-I converting enzyme
30 μM
IC50
RECORD: Rec_0164101 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
ACE-inhibitory peptide
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
ACE
30 μM
IC50
PaperInhibition of angiotensin-converting enzyme by synthetic peptide fragments of human ?-casein PMID1368540 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/1368540/
RECORD: Rec_0211687 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]; Bos taurus [Animal]
9606; 9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive
PMID1368540 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/1368540/
RECORD: Rec_0337797 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
ACE-inhibitory peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
ACE
30 μM
IC50
PaperIntegration of QSAR modelling and QM/MM analysis to investigate functional food peptides with antihypertensive activity
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