Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length460 amino acids

Chemical FormulaC2304H3600N582O659S19

DescriptionStandard

        MMFLWFVLVLVNLVSVATGTNAGVKVRLTQKGLEYGRQIGIASIQQKLRTIKVPDISGTETVDPIGKVQYSFTGMQIVNLGLPKSALGLVPDTGVMLSIGNGYINLHGNWRVKYLRIIKDSGSFDLAVSELTISTTIAVTNDDTGHPTVSMTNCAATVGSVNVKFHGGASWLYNLFSSFINKALCNALQKQICPLVADSIADINPHLKTLNVLAEVDQYGEFYNIGEHKEPPFSPIPFSFLSQDTDMIYIGVSAFTINSAGFVYNSAGALHSSGSPIRLNTKYTDDLFQIEKMYPGLMMKLLVETVKEPIVTFEPNNMTVQASKMFYNEFPFNQQEGSVSTHIYVTELKLAGNMTLNKIDISLAKSYVGPFQVTSLDNIFTIVLKVAVIPKVNAHLQEGYPLPAIGKMQLVNSRLQVLKVSLCHGDDQFVALLRWYGSPGFFDSGLQLICIFWSRFSFSC
    

Molecular Weight50605.97 Da

Isoelectric Point (pI)7.10

Net Charge (pH 7.0)0.25

Net Charge (pH 7.4) -0.61

Charge Density (pH 7.0) 0.0005

GRAVY Index0.19

Hydrophobic Moment 0.68

Boman Index0.19

Instability Index28.92

Aliphatic Index 99.96

Aromaticity 0.1022

Extinction Coeff. Reduced 51340.00

Extinction Coeff. Oxidized 51715.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0286771 VERIFIED: NO

Provenance & Taxonomy

OrganismCyprinus carpio [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria