Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length188 amino acids

Chemical FormulaC963H1444N212O283S11

DescriptionStandard

        IDDLAEVDYSLSSFPAVFQPFIDLDLKGTVFPAGNYTGSPYVVAPFSVTDQSDSMLLMAFSEYFFQTSSFAYYTAGAFNMTIAEEVIFCSTRSVFLYFFFFFCPAILQVAKYSVTPYPVMLKLMATEIPVISLEQDSFTVEIQGSMEVLAVLPDSTTQSLFTMNVAANSSISLNIFDQKLMGSLCLNR
    

Molecular Weight20871.73 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-12.25

Net Charge (pH 7.4) -12.54

Charge Density (pH 7.0) -0.0652

GRAVY Index0.49

Hydrophobic Moment 0.47

Boman Index0.29

Instability Index47.86

Aliphatic Index 90.74

Aromaticity 0.1543

Extinction Coeff. Reduced 13410.00

Extinction Coeff. Oxidized 13535.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7809.78

LogP -84.01

H-bond Donors 268.0

H-bond Acceptors 282.0

Rotatable Bonds 661.0

Heavy Atoms 1469.0

Ring Count 39.0

Amide Bonds 201.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0189972 VERIFIED: NO

Provenance & Taxonomy

OrganismTachuris rubrigastra [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria