Peptide Database

Peptide NameCirculin A

Function Ontology

Antimicrobial

Antiviral

Antiviral ▸ Anti-HIV

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Venom / Toxin ▸ General toxin ▸ Toxic

Standard StatusStandard

Sequence Length30 amino acids

Chemical FormulaC134H216N38O39S6

DescriptionStandard

        CGESCVWIPCISAALGCSCKNKVCYRNGIP
    

Molecular Weight3175.77 Da

Isoelectric Point (pI)8.33

Net Charge (pH 7.0)1.70

Net Charge (pH 7.4) 1.40

Charge Density (pH 7.0) 0.0567

GRAVY Index0.42

Hydrophobic Moment 0.26

Boman Index0.16

Instability Index24.06

Aliphatic Index 78.00

Aromaticity 0.0667

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1223.77

LogP -13.73

H-bond Donors 48.0

H-bond Acceptors 47.0

Rotatable Bonds 99.0

Heavy Atoms 217.0

Ring Count 5.0

Amide Bonds 31.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0072913 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configcyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antiviral Anti-HIV

TargetHuman erythrocytes

Activity20 μM

MethodHemolysis

RECORD: Rec_0210230 VERIFIED: YES