Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length71 amino acids

Chemical FormulaC354H569N101O91S8

DescriptionStandard

        MAQLLLLTVALLVLGHVPPGRTEFKRCWKGQGACRTYCTRQESFMHLCPDASLCCLAYALKPLPRPKPNHT
    

Molecular Weight7952.45 Da

Isoelectric Point (pI)9.30

Net Charge (pH 7.0)5.70

Net Charge (pH 7.4) 5.24

Charge Density (pH 7.0) 0.0803

GRAVY Index-0.00

Hydrophobic Moment 0.59

Boman Index0.04

Instability Index57.82

Aliphatic Index 86.62

Aromaticity 0.0704

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8855.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3020.53

LogP -25.27

H-bond Donors 110.0

H-bond Acceptors 108.0

Rotatable Bonds 251.0

Heavy Atoms 554.0

Ring Count 16.0

Amide Bonds 74.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0009399 VERIFIED: NO

Provenance & Taxonomy

OrganismMarmota marmota marmota [Animal]

FamilyDefensin

Structure & Mods

Configdisulfide-stabilized peptide with linear backbone [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin

MethodQualitative functional evidence

RECORD: Rec_0069176 VERIFIED: NO