Peptide Database

Peptide Nameapelin receptor early endogenous ligand

Function Ontology

Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide

Neurological / Signaling ▸ Receptor modulation ▸ Agonist

Neurological / Signaling ▸ Signaling peptide

Standard StatusStandard

Sequence Length32 amino acids

Chemical FormulaC170H291N63O39S4

DescriptionStandard

        QRPVNLTMRRKLRKHNCLQRRCMPLHSRVPFP
    

Molecular Weight3969.79 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)8.91

Net Charge (pH 7.4) 8.58

Charge Density (pH 7.0) 0.2785

GRAVY Index-1.01

Hydrophobic Moment 0.57

Boman Index-0.47

Instability Index129.23

Aliphatic Index 66.88

Aromaticity 0.0312

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1685.78

LogP -16.76

H-bond Donors 62.0

H-bond Acceptors 54.0

Rotatable Bonds 131.0

Heavy Atoms 276.0

Ring Count 7.0

Amide Bonds 35.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0030456 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyGtoPdb endogenous peptide ligand

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsN-linked glycosylation at Asn5 in the peptide sequence shown here (equivalent to Asn27 in the 54 amino acid precursor).

Bio-Activity Profile

Function

Receptor agonist Vasoactive Signaling peptide

Targetapelin receptor (Human)

Activity0.51 nM

MethodKd