Peptide Database

Peptide NameBeta-defensin 11 (BD-11) (mBD-11) (Defensin; beta 11)

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length77 amino acids

Chemical FormulaC384H604N102O102S12

DescriptionStandard

        MRTLCSLLLICCLLFSYTTPAVGDLKHLILKAQLARCYKFGGFCYNSMCPPHTKFIGNCHPDHLHCCINMKELEGST
    

Molecular Weight8666.31 Da

Isoelectric Point (pI)8.41

Net Charge (pH 7.0)2.85

Net Charge (pH 7.4) 2.23

Charge Density (pH 7.0) 0.0370

GRAVY Index0.27

Hydrophobic Moment 0.43

Boman Index0.16

Instability Index19.01

Aliphatic Index 88.70

Aromaticity 0.0909

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4970.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3201.38

LogP -26.23

H-bond Donors 119.0

H-bond Acceptors 122.0

Rotatable Bonds 280.0

Heavy Atoms 600.0

Ring Count 16.0

Amide Bonds 80.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0118559 VERIFIED: YES

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyBeta-defensin; Defensin

Tax ID10090

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic

RECORD: Rec_0316862 VERIFIED: YES