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MYP_138705
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Basic Information
MreB(19)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
9 amino acids
C54H88N14O10S2
Standard
Sequence
MLKKFRGMF
Physicochemical Analysis
1157.49 Da
11.17
2.50
2.28
0.2776
0.06
0.58
-0.04
-9.98
43.33
0.2222
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
410.06
-0.53
15.0
15.0
41.0
80.0
2.0
8.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0132507 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Staphylococcus aureus NCTC 8530
100 μM
MLC (2 h complete killing; CFU assay)
PaperThe N-terminal sequence of bacterial MreB is an antimicrobial peptide with rapid lethal activity (PMID:28230084) PMID28230084 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28230084/
RECORD: Rec_0142464 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Pseudomonas aeruginosa NCTC 6750
100 μM
MLC (2 h complete killing; CFU assay)
PaperThe N-terminal sequence of bacterial MreB is an antimicrobial peptide with rapid lethal activity (PMID:28230084) PMID28230084 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28230084/
RECORD: Rec_0148378 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Escherichia coli MG1655
15 μM
MLC (2 h complete killing; CFU assay)
PaperThe N-terminal sequence of bacterial MreB is an antimicrobial peptide with rapid lethal activity (PMID:28230084) PMID28230084 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28230084/
RECORD: Rec_0153691 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Escherichia coli MG1655
20 μM
MLC (2 h complete killing; CFU assay)
PaperThe N-terminal sequence of bacterial MreB is an antimicrobial peptide with rapid lethal activity (PMID:28230084) PMID28230084 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28230084/
RECORD: Rec_0206914 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hemolytic
human red blood cells
0 %
Hemolysis at 50 μM
PaperThe N-terminal sequence of bacterial MreB is an antimicrobial peptide with rapid lethal activity (PMID:28230084) PMID28230084 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28230084/
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