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MYP_138676
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Basic Information
Unnamed
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antiparasitic ▸ Antimalarial
Antiparasitic ▸ Antiprotozoal ▸ Antimalarial ▸ Anti-Plasmodium
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Enzyme modulation ▸ Enzyme inhibition ▸ Protease inhibition
Metabolic ▸ Uric acid metabolism ▸ Hypouricemic activity
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Standard
2 amino acids
C15H23N3O3
Standard
Sequence
FK
Physicochemical Analysis
293.36 Da
8.75
0.76
0.55
0.3795
-0.55
1.04
-0.15
-70.15
0.00
0.5000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
118.44
0.25
4.0
4.0
9.0
21.0
1.0
1.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0217913 VERIFIED: YES
Provenance & Taxonomy
Taraxacum mongolicum [Plant]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus
Paper蒲公英酶解抗菌肽的分析; Analysis of Antimicrobial Peptides in Taraxacum mongolicum Enzymatic Hydrolysis. [J].分子植物育种,2020,18(10):3388-3394. DOI:10.13271/j.mpb.018.003388. Evidence URLhttps://dramp.cpu-bioinfor.org/browse/All_Information.php?dataset=General&id=DRAMP37235
RECORD: Rec_0283815 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Mu=morpholine urea
VS=vinyl-sulfone,Ph=phenyl,HBr=HydrogenBromide
Bio-Activity Profile
Antimicrobial Antiparasitic Antiplasmodial Cysteine protease inhibitor
PaperParaPep: a web resource for experimentally validated antiparasitic peptide sequences and their structures PMID24923818 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24923818/
RECORD: Rec_0370752 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Protease/Proteasome inhibitor
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Morpholine urea
Vinyl sulfone
Bio-Activity Profile
Antimicrobial Cysteine protease inhibitor Antiparasitic Antimalarial
Plasmodium vinckei
0.05 μM
IC50; Fluorimetry (fluorescence by hydrolysis of benzyloxycarbonyl-Phe-Arg-7-amino-4-methyl-coumarin measured)
PaperAntimalarial effects of vinyl sulfone cysteine proteinase inhibitors PMID8807047 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8807047/
RECORD: Rec_0390092 VERIFIED: NO
Provenance & Taxonomy
Ipomoea batatas [Plant]; Solanum tuberosum [Plant]
4120; 4113
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive
RECORD: Rec_0393960 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
Angiotensin-converting enzyme (ACE)
265.43
IC50
PaperHuang G.-J., Lu T., Chiu C., Chen H., Wu C., Lin Y., Hsieh W., Liao J., Sheu M. Lin Y.. Sweet potato storage root defensin and its tryptic hydrolysates exhibited angiotensin converting enzyme inhibitory activity in vitro. Bot. Stud., 52, 257-264, 2011.
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