Peptide Database

Peptide NameDermaseptin-S8 (DRS-S8) (Dermaseptin DS VIII)

Function Ontology

Antimicrobial

Antiparasitic ▸ Antiprotozoal

Antiparasitic ▸ General antiparasitic ▸ Antiparasitic

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length79 amino acids

Chemical FormulaC382H632N102O123S4

DescriptionStandard

        MDILKKSLFLVLFLGLVSLSICEEEKRENEDEEKQEDDEQSEMKRALWKTMLKKLGTVALHAGKAALGAAADTISQGAQ
    

Molecular Weight8749.97 Da

Isoelectric Point (pI)4.93

Net Charge (pH 7.0)-4.40

Net Charge (pH 7.4) -4.71

Charge Density (pH 7.0) -0.0557

GRAVY Index-0.31

Hydrophobic Moment 0.53

Boman Index-0.03

Instability Index48.62

Aliphatic Index 96.46

Aromaticity 0.0380

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3672.36

LogP -33.68

H-bond Donors 126.0

H-bond Acceptors 124.0

Rotatable Bonds 314.0

Heavy Atoms 611.0

Ring Count 5.0

Amide Bonds 83.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0013974 VERIFIED: YES

Provenance & Taxonomy

OrganismPhyllomedusa sauvagei [Animal]

FamilyDermaseptin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antiparasitic Antiprotozoal Non-hemolytic

RECORD: Rec_0053712 VERIFIED: NO