Peptide Database

Peptide NameHolotricin-3

Function Ontology

Antimicrobial

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Anti-Candida

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length104 amino acids

Chemical FormulaC378H548N138O119S3

DescriptionStandard

        MNKLIILGLACIIAVASAMPYGPGDGHGGGHGGGHGGGHGNGQGGGHGHGPGGGFGGGHGGGHGGGGRGGGGSGGGGSPGHGAGGGYPGGHGGGHHGGYQTHGY
    

Molecular Weight9025.44 Da

Isoelectric Point (pI)8.10

Net Charge (pH 7.0)1.62

Net Charge (pH 7.4) 0.72

Charge Density (pH 7.0) 0.0156

GRAVY Index-0.52

Hydrophobic Moment 0.31

Boman Index0.28

Instability Index42.36

Aliphatic Index 33.85

Aromaticity 0.0481

Extinction Coeff. Reduced 5960.00

Extinction Coeff. Oxidized 5960.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3848.93

LogP -65.43

H-bond Donors 131.0

H-bond Acceptors 136.0

Rotatable Bonds 284.0

Heavy Atoms 638.0

Ring Count 23.0

Amide Bonds 107.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0367578 VERIFIED: YES

Provenance & Taxonomy

OrganismHolotrichia diomphalia [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Anti-Candida Non-hemolytic