Peptide Database

Peptide NameVT18-KKLV (VT18 peptide derivative)

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length18 amino acids

Chemical FormulaC101H143N21O21S3

DescriptionStandard

        VYPFMWGGAYCFCKAKLV
    

Molecular Weight2083.54 Da

Isoelectric Point (pI)8.82

Net Charge (pH 7.0)1.71

Net Charge (pH 7.4) 1.46

Charge Density (pH 7.0) 0.0950

GRAVY Index0.81

Hydrophobic Moment 0.29

Boman Index0.41

Instability Index14.47

Aliphatic Index 65.00

Aromaticity 0.2778

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8605.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 657.52

LogP -0.22

H-bond Donors 25.0

H-bond Acceptors 26.0

Rotatable Bonds 61.0

Heavy Atoms 146.0

Ring Count 7.0

Amide Bonds 17.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0401907 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Hemolytic

TargetHuman RBC

Activity500 μg/mL

MethodHemolysis

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