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MYP_138531
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Basic Information
[Leu]8 -Dec-NH2
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Standard
11 amino acids
C58H108N14O15
Standard
Sequence
SLLSLIRLLIT
Physicochemical Analysis
1241.56 Da
9.47
0.46
0.25
0.0418
1.93
0.49
0.47
9.09
248.18
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
476.91
-1.80
18.0
16.0
42.0
87.0
0.0
10.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0331025 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Candida albicans MDM8
12.5
MIC
PMID28795464 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28795464/
RECORD: Rec_0337617 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
Human red blood cells
50
MHC
PaperPubMed PMID: 30013694 PMID30013694 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30013694/
RECORD: Rec_0380099 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hemolytic
Human RBCS
50 μM
Hemolysis
PMID28795464 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28795464/
RECORD: Rec_0392729 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Anticancer
RECORD: Rec_0406713 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
MCF-7
50 μM
IC50
PaperPubMed PMID: 30013694 PMID30013694 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30013694/
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