Peptide Database

Peptide NameRApoE (133-150)

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC111H206N42O22S

DescriptionStandard

        PMLRVRLASHLRKLRKRLLR
    

Molecular Weight2513.16 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)8.04

Net Charge (pH 7.4) 7.93

Charge Density (pH 7.0) 0.4022

GRAVY Index-0.48

Hydrophobic Moment 0.73

Boman Index-0.50

Instability Index56.30

Aliphatic Index 136.50

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1074.58

LogP -7.46

H-bond Donors 43.0

H-bond Acceptors 32.0

Rotatable Bonds 90.0

Heavy Atoms 176.0

Ring Count 2.0

Amide Bonds 19.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0320752 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetEscherichia coli ATCC 25922

Activity6.25 μM

MethodMIC

RECORD: Rec_0422439 VERIFIED: YES