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MYP_138499
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Basic Information
Qa
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Standard
12 amino acids
C88H124N26O13
Standard
Sequence
IHKFWRRWFKHI
Physicochemical Analysis
1754.09 Da
12.00
3.93
3.63
0.3277
-0.87
0.89
-0.17
158.74
65.00
0.3333
11000.00
11000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
648.20
0.47
25.0
19.0
55.0
127.0
8.0
11.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0312468 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli UB1005
8 μM
MIC
PMID30538681 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30538681/
RECORD: Rec_0333684 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli ATCC 25922
16 μM
MIC
PMID30538681 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30538681/
RECORD: Rec_0337028 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Bacillus subtilis CMCC 63501
32 μM
MIC
PaperShort Symmetric-End Antimicrobial Peptides Centered on beta-Turn Amino Acids Unit Improve Selectivity and Stability PMID30538681 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30538681/
RECORD: Rec_0342185 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Cytotoxic
IPEC-J2 intestinal epithelial cells
61 % cell viability
MTT cell-viability assay
PaperShort Symmetric-End Antimicrobial Peptides Centered on beta-Turn Amino Acids Unit Improve Selectivity and Stability PMID30538681 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30538681/
RECORD: Rec_0361921 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Salmonella Typhimurium ATCC 7731
16 μM
MIC
PMID30538681 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30538681/
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