Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length196 amino acids

Chemical FormulaC989H1564N266O267S9

DescriptionStandard

        PKTLPMAHEPMLLLAVTELVANSATFTYFTAGALRRNLSSDMLPRQFPLQLRTKSMEVFSPELQERYPDQPMELHLWARQQPLLSCHPDALHGTLFSSAEAFVVLPNATRVPAFLLNIDANVTGKPTISRNRLGGTVRLTGLVPNPELAWTPLPALGWAQDLPIPQVKRLETLLKFGLWLFGVPRANSKCCPCPVP
    

Molecular Weight21741.21 Da

Isoelectric Point (pI)9.10

Net Charge (pH 7.0)4.29

Net Charge (pH 7.4) 3.94

Charge Density (pH 7.0) 0.0219

GRAVY Index0.01

Hydrophobic Moment 0.55

Boman Index0.10

Instability Index52.01

Aliphatic Index 96.07

Aromaticity 0.0765

Extinction Coeff. Reduced 24980.00

Extinction Coeff. Oxidized 25230.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8344.87

LogP -100.34

H-bond Donors 285.0

H-bond Acceptors 284.0

Rotatable Bonds 681.0

Heavy Atoms 1531.0

Ring Count 46.0

Amide Bonds 211.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0086657 VERIFIED: NO

Provenance & Taxonomy

OrganismSterrhoptilus dennistouni [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria