Peptide Database

Peptide NameLipotropin beta

Function Ontology

Antimicrobial

Cardiovascular

Hormonal / Endocrine ▸ Hormone peptide

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide precursor

Regulatory peptide ▸ Biological modulation

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length71 amino acids

Chemical FormulaC361H566N102O111S

DescriptionStandard

        ELEGERPLGLEQVLESDAEKDDGPYRVEHFRWSNPPKDKRYGGFMTSEKSQTPLVTLFKNAIIKNAHKKGQ
    

Molecular Weight8143.04 Da

Isoelectric Point (pI)7.03

Net Charge (pH 7.0)0.03

Net Charge (pH 7.4) -0.27

Charge Density (pH 7.0) 0.0004

GRAVY Index-1.09

Hydrophobic Moment 0.49

Boman Index-0.21

Instability Index25.67

Aliphatic Index 60.42

Aromaticity 0.0845

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3473.49

LogP -34.48

H-bond Donors 117.0

H-bond Acceptors 114.0

Rotatable Bonds 276.0

Heavy Atoms 575.0

Ring Count 14.0

Amide Bonds 76.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0141789 VERIFIED: NO

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyPOMC

Tax ID10090

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone precursor Neuropeptide precursor

RECORD: Rec_0197588 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/

RECORD: Rec_0409482 VERIFIED: NO

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyLipotropin

Tax ID10090

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Hormone Endocrine Neuropeptide Neuromodulator Cardiovascular Metabolic regulation Physiological regulation Receptor modulation Immunomodulatory

Half-LifeMammalian: 1 hour; Yeast: 30 min; E. coli: >10 hour