Peptide Database

Peptide Namehuman GIP(1-30)NH2

Function Ontology

Hormonal / Endocrine ▸ Hormonal activity

Metabolic ▸ Glucose metabolism ▸ Antidiabetic

Neurological / Signaling ▸ Receptor modulation ▸ Agonist

Standard StatusStandard

Sequence Length30 amino acids

Chemical FormulaC162H239N39O48S

DescriptionStandard

        YAEGTFISDYSIAMDKIHQQDFVNWLLAQK
    

Molecular Weight3532.93 Da

Isoelectric Point (pI)4.66

Net Charge (pH 7.0)-2.15

Net Charge (pH 7.4) -2.41

Charge Density (pH 7.0) -0.0717

GRAVY Index-0.23

Hydrophobic Moment 0.35

Boman Index0.12

Instability Index28.28

Aliphatic Index 84.67

Aromaticity 0.1667

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1426.44

LogP -10.56

H-bond Donors 48.0

H-bond Acceptors 48.0

Rotatable Bonds 116.0

Heavy Atoms 250.0

Ring Count 7.0

Amide Bonds 33.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0290279 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyGtoPdb peptide ligand

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-Termamidated

Other ModsC-terminal amidation

Bio-Activity Profile

Function

Receptor agonist Antidiabetic Hormonal activity

TargetGIP receptor (Human)

Activity0.89 nM

MethodKi