Peptide Database

Peptide NameCYO13_VIOOD

Function Ontology

Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive

Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory

Neurological / Signaling ▸ Signaling peptide

Other / Curated residual function label ▸ Generic enzyme inhibition annotation

Standard StatusStandard

Sequence Length115 amino acids

Chemical FormulaC556H908N138O164S9

DescriptionStandard

        CSCKSKVCYRNSLDNEDVINALLKSKTVISNPIIEEAFLKNSNGLNGIPCGESCVWIPCISAAIGMDAKKMFVALVLIATFALPSLATFEKDFITPETIQAILKKSAPLSNIMLE
    

Molecular Weight12438.57 Da

Isoelectric Point (pI)6.46

Net Charge (pH 7.0)-0.28

Net Charge (pH 7.4) -0.61

Charge Density (pH 7.0) -0.0024

GRAVY Index0.39

Hydrophobic Moment 0.48

Boman Index0.19

Instability Index31.87

Aliphatic Index 109.48

Aromaticity 0.0609

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4807.89

LogP -43.15

H-bond Donors 167.0

H-bond Acceptors 173.0

Rotatable Bonds 416.0

Heavy Atoms 867.0

Ring Count 14.0

Amide Bonds 123.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0032458 VERIFIED: YES

Provenance & Taxonomy

OrganismViola odorata [Plant]

FamilyCyclotide

Tax ID97441

Structure & Mods

Confighead-to-tail cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond reported, sites not specified

Bio-Activity Profile

Function

Signaling Enzyme inhibitory ACE inhibitory Antihypertensive

TargetAngiotensin-converting enzyme