Peptide Database

Peptide NameColicin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length525 amino acids

Chemical FormulaC2472H3986N718O757S8

DescriptionStandard

        MPNEDTINVNGGSGGKDSGIHWGGGGNGGGNGSNSSGANLSSTPEAQKPAAYGVPAVIGVYDGMWGFTLFTKTTLQEAMQAALTRIEQGAVAAVPLAGRLLGATIGALIPSEIAKDVPRMMATAHLVNSLPFDKVSTTPPSALPTQKATVVHTRIADVVDEDGKQHIAVVKSKNMPMSVPVVDAKPTKRPGVYTAGVVPGKPDLHVKVDAGKAPAVSQSQPKGIQKEQGASRYPGFTTGQNTHEAIVRFPDGKSPPIYVSVTEVSTPDQVKKRLEEEKRRTLAWALNSPVEAAAKEDKEAGDQLSRAQADIVKAQERLNKALQAIPQRNSDLDAANKGVEAMLKWVKQVEVYAHDPDHPGHRVFLQAGYKLGLAKEKAKVSKAALDAAIKEKADAEKALAIAVESRKQKEQKKKASEQKLADEKKKPRKGAKDYGHDYHPVPKTEEIKGLGDLTKGAPKTPKQNGGGKRPRWYGDKKSKIYEWDSQHGELEGYRGSDGSHLGAFDPATGKQVKGPDPKRNIKKYL
    

Molecular Weight56132.97 Da

Isoelectric Point (pI)9.51

Net Charge (pH 7.0)19.68

Net Charge (pH 7.4) 18.63

Charge Density (pH 7.0) 0.0375

GRAVY Index-0.67

Hydrophobic Moment 0.72

Boman Index-0.08

Instability Index36.95

Aliphatic Index 70.86

Aromaticity 0.0495

Extinction Coeff. Reduced 52370.00

Extinction Coeff. Oxidized 52370.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0367872 VERIFIED: YES

Provenance & Taxonomy

OrganismEnterobacter hormaechei [Bacterium]

Structure & Mods

Configlinear polypeptide/propeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibiotic Bacteriocin Non-hemolytic Non-ribosomal

TargetEscherichia coli