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MYP_138288
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Basic Information
Maculatin 3.1
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
26 amino acids
C121H213N31O39
Standard
Sequence
GLLQTIKEKLESLESLAKGIVSGIQA
Physicochemical Analysis
2726.17 Da
6.23
-0.23
-0.45
-0.0090
0.26
0.57
0.16
17.38
138.85
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1147.88
-10.65
39.0
39.0
99.0
191.0
0.0
27.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0133098 VERIFIED: YES
Provenance & Taxonomy
Litoria genimaculate [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anticancer
Lactococcus lactis
>100 μg/mL
MIC
PaperThe maculatin peptide from the skin glands of the tree frog Litoria genimaculata. A comparison of the structures and antibacterial activities of maculatin 1.1 and caerin 1.1
RECORD: Rec_0138656 VERIFIED: YES
Provenance & Taxonomy
Ranoidea genimaculata [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Non-hemolytic
PMID9620615 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9620615/
RECORD: Rec_0189596 VERIFIED: YES
Provenance & Taxonomy
Litoria genimaculata [Animal]
Maculatin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
S.uberis.
PMID9620615 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9620615/
RECORD: Rec_0259291 VERIFIED: NO
Provenance & Taxonomy
Fringed tree [Animal]
Maculatin
33208
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
PaperAPD2: the updated antimicrobial peptide database and its application in peptide design PMID18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18957441/
RECORD: Rec_0265392 VERIFIED: YES
Provenance & Taxonomy
Litoria genimaculata [Animal]
Maculatin
Structure & Mods
ribosomal mature linear peptide [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial
PaperM.A. Apponyi et al. / Peptides 25 (2004) 1035-1054. Host-defence peptides of Australian anurans: structure, mechanism of action and evolutionary significance PMID15203252 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15203252/
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