Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length67 amino acids

Chemical FormulaC350H572N104O86S8

DescriptionStandard

        MKLLLLALAALLLLSQLTPGDTQKCWNLRGRCRHRCSRKERVYVYCTNSKMCCVKPKYQPKGRPWPF
    

Molecular Weight7869.45 Da

Isoelectric Point (pI)10.07

Net Charge (pH 7.0)11.52

Net Charge (pH 7.4) 11.15

Charge Density (pH 7.0) 0.1720

GRAVY Index-0.37

Hydrophobic Moment 0.48

Boman Index-0.14

Instability Index30.31

Aliphatic Index 81.49

Aromaticity 0.0896

Extinction Coeff. Reduced 15470.00

Extinction Coeff. Oxidized 15845.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3087.79

LogP -25.31

H-bond Donors 116.0

H-bond Acceptors 107.0

Rotatable Bonds 259.0

Heavy Atoms 548.0

Ring Count 14.0

Amide Bonds 71.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0057454 VERIFIED: NO

Provenance & Taxonomy

OrganismProlemur simus [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence