MYP_138208
Basic Information
Esculentin-2A (Frogs, amphibians, animals)
Antimicrobial
Antimicrobial Antibacterial
Antimicrobial Antibacterial Anti-Gram-negative
Antimicrobial Antibacterial Anti-Gram-positive
Toxicity / Safety Blood cell toxicity Hemolysis Hemolytic
Toxicity / Safety Cytolysis / cell lysis Cytolytic activity
Standard
37 amino acids
C168H295N45O44S2
Standard
Sequence
GILSLVKGVAKLAGKGLAKEGGKFGLELIACKIAKQC
Physicochemical Analysis
3713.54 Da
9.70
4.74
4.49
0.1281
0.54
0.60
0.21
17.66
124.05
0.0270
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1430.98
-10.91
51.0
51.0
135.0
259.0
1.0
37.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0391964 VERIFIED: YES
Provenance & Taxonomy
Rana esculenta [Animal]
Esculentin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus Cowan 1
0.8 μM
MIC
RECORD: Rec_0394531 VERIFIED: YES
Provenance & Taxonomy
Rana esculenta [Plant]
Esculentin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Cyclization
31-37
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Bacillus megaterium Bm11
0.2 μM
MIC
RECORD: Rec_0412986 VERIFIED: YES
Provenance & Taxonomy
Rana esculenta [Animal]
Esculentin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa ATCC15692
3.5 μM
MIC
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