Peptide Database

Peptide NameApl_AvBD-2

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length41 amino acids

Chemical FormulaC199H313N61O49S7

DescriptionStandard

        PGLSSPRRDMFFCRKGSCHFGRCPIPLVKVGSCFGFRSCCK
    

Molecular Weight4568.45 Da

Isoelectric Point (pI)9.70

Net Charge (pH 7.0)6.98

Net Charge (pH 7.4) 6.78

Charge Density (pH 7.0) 0.1704

GRAVY Index-0.05

Hydrophobic Moment 0.59

Boman Index-0.06

Instability Index74.38

Aliphatic Index 42.68

Aromaticity 0.1220

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 375.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1741.65

LogP -19.01

H-bond Donors 70.0

H-bond Acceptors 64.0

Rotatable Bonds 146.0

Heavy Atoms 316.0

Ring Count 10.0

Amide Bonds 40.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0326717 VERIFIED: YES

Provenance & Taxonomy

OrganismTyto alba [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)