Peptide Database

Peptide NameBrevinin-2WY2

Function Ontology

Antimicrobial

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length74 amino acids

Chemical FormulaC356H580N90O117S6

DescriptionStandard

        MFTSKKPLLVLFFLGTISLSFCEEERNADEDDGEMTEEEKRGLMSTLKDFGKTAAKEIAQSLLSTASCKLAKTC
    

Molecular Weight8185.34 Da

Isoelectric Point (pI)4.88

Net Charge (pH 7.0)-3.51

Net Charge (pH 7.4) -3.80

Charge Density (pH 7.0) -0.0474

GRAVY Index-0.23

Hydrophobic Moment 0.64

Boman Index-0.02

Instability Index47.32

Aliphatic Index 75.27

Aromaticity 0.0676

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3365.09

LogP -34.60

H-bond Donors 120.0

H-bond Acceptors 120.0

Rotatable Bonds 287.0

Heavy Atoms 569.0

Ring Count 6.0

Amide Bonds 75.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0262414 VERIFIED: NO

Provenance & Taxonomy

OrganismAmolops wuyiensis [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Amphibian defense peptide Antimicrobial Non-hemolytic Non-ribosomal

MethodQualitative functional evidence