Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length62 amino acids

Chemical FormulaC301H486N88O92S6

DescriptionStandard

        SYFEQKSKAVQFLSVGLSPNWGTNRLSKMDGRCEVECLSFEDKIGGCRAELTPLCCKKRKNN
    

Molecular Weight7002.00 Da

Isoelectric Point (pI)8.95

Net Charge (pH 7.0)3.42

Net Charge (pH 7.4) 3.12

Charge Density (pH 7.0) 0.0551

GRAVY Index-0.61

Hydrophobic Moment 0.53

Boman Index-0.17

Instability Index33.38

Aliphatic Index 61.29

Aromaticity 0.0806

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7240.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2968.08

LogP -33.75

H-bond Donors 108.0

H-bond Acceptors 102.0

Rotatable Bonds 241.0

Heavy Atoms 487.0

Ring Count 8.0

Amide Bonds 67.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0226183 VERIFIED: NO

Provenance & Taxonomy

OrganismCanis lupus familiaris [Animal]

FamilyDefensin

Tax ID9615

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal