Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length456 amino acids

Chemical FormulaC2298H3585N597O656S21

DescriptionStandard

        MMARPYCVVVALLLLAEVTRFGEGTPNPEIVGKITRKGLKYARQYGIATLKKELSAIKLPDFSGSFRICLIGNVNYVFSGLRIRRFVLLNSNLRLHTEQGIRASLFNNYVSVSGNWKVQKSFVNLYGTFDLSVDDISISVSLNFGKDQSGQPTASLTHCSNSIGQVSIEISGYLRSWHDTEGNSKGLTDKESNEEITLMVNQIAGIDYSLVGAPKACTCPSRKGEFFGQNGSFSVPFDAPLIRLPEKHDYMIYFAVSEYVFNMASRVYHQAGLMNFTIQNKHNLMQFINHQLAEKWWKPYVSPGCLNSKSTPLTTLLSCFSSNFLLRLLQIPLDSPVLLNTNSFWAIVPKSFETSPESAPFLMFTPGNVTFMPVMDIQAFALMPNSSDCKALFHLRAVVLMESILNDYALHIIYPTLNAKLEEGSPLPLPKDIYLNSLELQVHKVSEKCSLGGGAL
    

Molecular Weight50745.02 Da

Isoelectric Point (pI)8.45

Net Charge (pH 7.0)4.32

Net Charge (pH 7.4) 3.36

Charge Density (pH 7.0) 0.0095

GRAVY Index0.03

Hydrophobic Moment 0.83

Boman Index0.12

Instability Index39.91

Aliphatic Index 94.69

Aromaticity 0.1031

Extinction Coeff. Reduced 51340.00

Extinction Coeff. Oxidized 51840.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0341770 VERIFIED: NO

Provenance & Taxonomy

OrganismCamelus ferus (Wild bactrian camel) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria