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MYP_138139
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Basic Information
VK25 (histone derived; reptiles; animals)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Standard
14 amino acids
C71H130N20O17
Standard
Sequence
SPKKTKPVKPKKVA
Physicochemical Analysis
1535.92 Da
10.70
5.45
5.24
0.3896
-1.39
0.18
-0.43
35.54
48.57
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
611.83
-5.30
20.0
23.0
52.0
108.0
3.0
13.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0062899 VERIFIED: YES
Provenance & Taxonomy
blood plasma,Komodo dragon,Varanus komodoensis [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial
Active against P
PMID28164707 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28164707/
RECORD: Rec_0092099 VERIFIED: YES
Provenance & Taxonomy
Varanus komodoensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa PAO1
17.7 μM
EC50
PMID28649410 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28649410/
RECORD: Rec_0149991 VERIFIED: YES
Provenance & Taxonomy
blood plasma,Komodo dragon,Varanus komodoensis [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial
eruginosa ATCC9027 and S
3.2 μM
EC50
PMID28164707 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28164707/
RECORD: Rec_0165191 VERIFIED: YES
Provenance & Taxonomy
blood plasma,Komodo dragon,Varanus komodoensis [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus ATCC 25923
2.5 μM
EC50
PMID28164707 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28164707/
RECORD: Rec_0209088 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct based on Varanus komodoensis [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
P. eruginosa ATCC 9027
3.2 μM
EC50
PaperDiscovery of Novel Antimicrobial Peptides from Varanus komodoensis (Komodo dragon) by Large Scale Analyses and De Novo-Assisted Sequencing using Electron Transfer Dissociation Mass Spectrometry
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