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MYP_138102
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Basic Information
Cholecystokinin-12
Gastrointestinal bioactivity
Hormonal / Endocrine ▸ Hormone peptide
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuromuscular and muscle activity ▸ Myotropic activity
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Cell-cell communication
Standard
12 amino acids
C68H94N16O21S2
Standard
Sequence
ISDRDYMGWMDF
Physicochemical Analysis
1535.70 Da
4.05
-2.24
-2.44
-0.1865
-0.61
0.30
-0.00
63.23
32.50
0.2500
6990.00
6990.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
613.47
-3.49
22.0
21.0
48.0
107.0
4.0
11.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0195371 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Gastrin/cholecystokinin
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Tyr6 Sulfotyrosine
Bio-Activity Profile
Hormone Gastrointestinal Neuropeptide
PMID5410106 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/5410106/
RECORD: Rec_0227991 VERIFIED: YES
Provenance & Taxonomy
Macaca fascicularis [Animal]
Gastrin/cholecystokinin
9541
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Tyr6 Sulfotyrosine
Bio-Activity Profile
Hormone Gastrointestinal Neuropeptide
PMID5410106 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/5410106/
RECORD: Rec_0258811 VERIFIED: NO
Provenance & Taxonomy
Homo sapiens [Animal]
Cholecystokinin
9606
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Amidation
6:Sulfotyrosine
Bio-Activity Profile
Hormone Endocrine Neuropeptide Neuromodulator Myotropic Receptor modulation
CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion
Mammalian: 20 hour; Yeast: 30 min; E. coli: >10 hour
RECORD: Rec_0291924 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Gastrin/cholecystokinin
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Tyr6 Sulfotyrosine
Bio-Activity Profile
Hormone Gastrointestinal Neuropeptide
PMID5410106 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/5410106/
RECORD: Rec_0368326 VERIFIED: YES
Provenance & Taxonomy
Canis familiaris [Animal]
Gastrin/cholecystokinin
9615
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Tyr6 Sulfotyrosine
Bio-Activity Profile
Hormone Gastrointestinal Neuropeptide
PMID2430967 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/2430967/
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