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MYP_138045
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Basic Information
GW-A5 (De novo synthesis)
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
20 amino acids
C102H171N25O27
Standard
Sequence
GATYAKKIIKTITKIATTAW
Physicochemical Analysis
2179.60 Da
10.18
3.76
3.54
0.1878
0.17
0.84
0.17
4.36
98.00
0.1000
6990.00
6990.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
857.47
-6.40
32.0
31.0
72.0
154.0
3.0
19.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0187196 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
PaperDesign and synthesis of cationic antimicrobial peptides with improved activity and selectivity against Vibrio spp. Int J Antimicrob Agents. 2008 Aug;32(2):130-8. doi: 10.1016/j.ijantimicag.2008.04.003. PMID: 18586467. PMID18586467 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18586467/
RECORD: Rec_0196695 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Enterobacter aerogenes (BCRC 10370)
64 μg/mL
MIC
PaperDesign and synthesis of cationic antimicrobial peptides with improved activity and selectivity against Vibrio spp. Int J Antimicrob Agents. 2008 Aug;32(2):130-8. doi: 10.1016/j.ijantimicag.2008.04.003. PMID: 18586467. PMID18586467 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18586467/
RECORD: Rec_0215328 VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID28750089 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28750089/
RECORD: Rec_0229308 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Yersinia enterocolitica (BCRC 13999)
128 μg/mL
MIC
PaperDesign and synthesis of cationic antimicrobial peptides with improved activity and selectivity against Vibrio spp. Int J Antimicrob Agents. 2008 Aug;32(2):130-8. doi: 10.1016/j.ijantimicag.2008.04.003. PMID: 18586467. PMID18586467 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18586467/
RECORD: Rec_0231860 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Anticancer
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